Women with Turner Syndrome (TS) are a distinctive group of women who require specialized medical and obstetrical/gynecological care. TS is found in approximately 1 in 2,500 pregnancies and is the result of the loss or partial loss of an X chromosome. Normally women’s chromosomes are 45XX and with TS it will be 45X. Because of this missing chromosome women with TS can look slightly different and can have an array of possible medical conditions such as:
cardiovascular disease which could be the result of a congenital anomaly
Pediatricians and pediatric endocrinologists usually follow these patients closely during childhood and adolescence, initiating estrogen to begin puberty and normal development. Conception and pregnancy offer unique conditions which will require individualized intense care by a team of specialists and preconception counseling is a must. Because of the higher risks for various medical conditions, TS patients need to be followed carefully throughout their lives.
…..Many menopausal women suffer from osteoporosis. Osteoporosis is the thinning of bones which causes them to become weak, brittle, and more susceptible to fractures. Women have an increased risk of osteoporosis throughout their lifetime. Risk factors include:
Low body weight
…..There are various methods of prevention and treatment for osteoporosis. There are medications such as the bisphosphonates (Fosamax) and selective estrogen receptor modulators (Evista). Supplements such as calcium and Vitamin D are important additives. Helpful lifestyle changes include the cessation of smoking, decreased alcohol use, and weight-bearing exercises.
…..Evista is a medication used to treat osteoporosis in the selective estrogen receptor modulator class. It mimics the beneficial effects of estrogen by increasing bone density. Many studies have also shown that Evista decreases the risk of certain types of breast cancer. The side effects of Evista are hot flushes, leg cramps, and infrequent blood clots or strokes.
…..Speak to your health care provider to see if Evista can be of benefit for you to treat osteoporosis and prevent breast cancer.
It has been a common thought that when using a medication for a particular problem, always try to use the lowest dose possible so potential side effects would be decreased. In terms of oral contraceptives, the dosage of these medications has been gradually reduced over the years in order to decrease the risks of abnormal blood clotting and breast concerns. Now the new very low dose oral contraceptive formulas are being reviewed due to their potential effects on long-term bone health when used in young women.
Bone mass increases greatly in young women. It is an important buildup which can have great effects later on in life.
Osteoporosis is a common problem especially in older women, and it is a condition of low bone mass, increasing the possibility of fractures. Recent studies have indicated that young women who have been on the very low dose oral contraceptives may have a decrease in the buildup of their bone mass, setting them up for potential problems as they grow older.
As always, before beginning any medication, you must have a good discussion with your health care provider about that medication. When considering an oral contraceptive, ask questions about the various dosages available so the best choice can be made.